1. Xaiv cov excipients kom raug
Tom qab ntxiv ib co hydrated magnesium silicate rau hauv tshuaj ntsuab granules, lub kaum sab xis ntawm repose tau txo kom meej meej, fluidity tau nce thiab sau hnyav variation tau nqaim.Hauv lwm qhov xwm txheej, Avicel PH302 raws li ib qho diluent kuj txo qis qhov hnyav ntawm qhov hloov pauv ntawm cyclandelate capsule thiab ua rau kom cov hmoov av ntau dua.
2. Optimize cov formulations
Tsis yog kev hloov pauv ntawm excipients yuav daws tau qhov teeb meem kev hloov pauv, qhov loj ntawm granule thiab cov tshuaj muaj pes tsawg leeg kuj cuam tshuam rau qhov ua tiav.Qee tsab xov xwm hais txog ethanol sib xyaw hauv cov txheej txheem granulation yuav txo qis adsorption ntawm cov hmoov rau cov phaj muab tub lim.
3. Kho qhov muab tub lim
Capsule muab tub lim yog qhov tseem ceeb hauv kev tsim cov tshuaj ntsuab tshuaj ntsiav.Qee cov fillers ntsuas cov hmoov los ntawm lub ntsuas phaj.Thicker lub phaj yog, hmoov ntau dua thiab hnyav dua lub capsule.Txiav txim siab lub thickness ntawm lub phaj ntsuas thiab kho qhov tob ntawm lub filling stick kom hloov qhov ceev thiab conformity ntawm cov hmoov kem.Raws li qhov no, capsule shells nyob rau hauv ntau qhov sib txawv xav tau cov phaj tsim nyog thiab qhov tob ntawm lub filling stick raws li.Caij nplooj ntoos hlav, siab thiab cov qauv kuj cuam tshuam rau kev ua tiav.
4. Kev tswj ib puag ncig
Tag nrho cov tshuaj ntsiav, tshwj xeeb tshaj yog cov tshuaj ntsuab tshuaj ntsuab yuav tsum tau muab cia rau hauv qhov chaw ruaj khov: kub 18-26℃,Cov av noo 45% -65% thiab huab cua huv heev.
5. Nrhiav machinery kev daws teeb meem
Cov cuab yeej saib xyuas cov txheej txheem thiab cov cuab yeej ntsuas cov txiaj ntsig tuaj yeem siv tau rau kev tswj lub cev hnyav.Yog tias koj nkees txog cov txheej txheem saum toj no, txoj hauv kev yooj yim dua yog nrhiav lub tshuab zoo rau kev tsim tshuaj.
Xa koj cov lus rau peb:
Post lub sij hawm: Oct-16-2017